Norifumi Yamamoto(Professor)

I’m a Professor at Chiba Institute of Technology in Japan. My major is Computational Chemistry. I’m working on the analysis and design of molecules using computational methods such as Quantum Chemistry, Molecular Dynamics, and Machine Learning.


  • Department of Applied Chemistry, Faculty of Engineering, Chiba Institute of Technology
  • 2-17-1 Tsudanuma, Narashino, Chiba 275-0016, Japan


  • Computational Chemistry (Quantum Chemistry, Molecular Dynamics, Machine Learning)

Professional Experiences

  • April 2022, Chiba Institute of Technology, Department of Applied Chemistry, Faculty of Engineering, Professor
  • April 2016, Chiba Institute of Technology, Department of Applied Chemistry, Faculty of Engineering, Associate Professor
  • April 2012, Chiba Institute of Technology, Department of Life and Environmental Sciences, Faculty of Engineering, Assistant Professor
  • July 2010, Nagoya University, Graduate School of Information Science, Assistant Professor
  • April 2007, Gifu University, Center for Emerging Infectious Diseases, Assistant Professor
  • April 2004, The University of Tokyo, Graduate School of Arts and Science, Postdoctoral Fellow of the Japan Society for the Promotion of Science (JSPS)


  • March 2004, Kyushu University, Ph.D., Science
  • March 2001, Kyushu University, M.S., Chemistry
  • March 1999, Kyushu University, B.S., Chemistry

Recent Publications

  1. Norifumi Yamamoto, Gen-ichi Sampei, Gota Kawai, Free-energy profile analysis of the catalytic Reaction of glycinamide ribonucleotide synthetase, Life, Vol. 12, e281 (2022)
  2. Mohini Yadav, Manabu Igarashi, Norifumi Yamamoto, Theoretical insights into the molecular mechanism of I117V mutation in neuraminidase mediated reduction of oseltamivir drug susceptibility in A/H5N1 influenza virus, PeerJ Phys. Chem., Vol. 3, e19 (2021)
  3. Kota Honda, Rintaro Fujikawa, Xiao MA, Norifumi Yamamoto, Kota Fujiwara, Akiko Kaneko, Yutaka Abe, The formation and growth model of a CO2 hydrate layer based on molecular dynamics, AIChE Journal, Vol. 68, e17406 (2021)
  4. Mohini Yadav, Manabu Igarashi, Norifumi Yamamoto, Dynamic residue interaction network analysis of the oseltamivir binding site of N1 neuraminidase and its H274Y mutation site conferring drug resistance in influenza A virus, PeerJ, Vol. 9, p. e11552 (2021)
  5. Kei Moritsugu, Norifumi Yamamoto, Yasushige Yonezawa, Shin-ichi Tate, Hiroshi Fujisaki, Path ensembles for Pin1-catalyzed cis-trans isomerization of a substrate calculated by weighted ensemble simulations, J. Chem. Theory Comp., Vol. 17, pp. 2522-2529 (2021)
  6. Norifumi Yamamoto, Free energy profile analysis to identify factors activating the aggregation-induced emission of a cyanostilbene derivative, Phys. Chem. Chem. Phys., Vol. 23, pp. 1317-1324 (2021)
  7. Norifumi Yamamoto, Free energy profile analysis for the aggregation-induced emission of diphenyldibenzofulvene, J. Phys. Chem. A, Vol. 124, pp. 4939-4945 (2020)
  8. Yoshinori Shibanuma, Naoki Nemoto, Norifumi Yamamoto, Gen-Ichi Sampei, Gota Kawai, Crystal structure of adenylate kinase from an extremophilic archaeon Aeropyrum pernix with ATP and AMP, J. Biochem., Vol. 168, pp. 223-229 (2020)

Society Memberships

  • The Chemical Society of Japan
  • Japan Society for Molecular Science
  • Japan Society of Computer Chemistry
  • The Biophysical Society of Japan
  • The Chem-Bio Informatics Society

Academic Editor

  • PeerJ Physical Chemistry


  • JSPS Grant-in-Aid for Scientific Research (C), 2017-2020, 2017-2020
  • JSPS Grant-inAid for Young Scientists (B), 2008–2010, 2011–2013
  • Grant-in-Aid for JSPS Fellows, 2004–2006